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KMID : 0380020070220040265
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Korean Journal of Biotechnology and Bioengineering
2007 Volume.22 No. 4 p.265 ~ p.269
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In Vitro Glucose and Bile Acid Retardation Effect of Fucoidan from Laminaria japonica
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Baek Jin-Hong
Hur Won
Lee Shin-Young
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Abstract
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Fucoidan from sea tangle (Laminaria japonica) was isolated by hot water extraction, and partially purified. The in-vitro glucose and bile acid retarding effects of the partially purified fucoidan were investigated. Fucoidan exhibited 27.0621.42% of retarding index for glucose and 33.5027.02% of retarding index for bile acid during in vitro dialysis experiment for 2 hours. These retarding effects on glucose and bile acid diffusion was considered as a relatively good or very good, suggesting the prevention from diabetes and arteriosclerosis of some extent.
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KEYWORD
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Fucoidan, Laminaria japonica, in-vitro glucose and bile acid retarding effect
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